August 26, 2019
china

The Changing Face of Regulations and Market Access in China

China is rapidly emerging as world’s fastest growing pharmaceutical industry. The market  is poised to reach $175B by 20221. Faster regulatory approvals and widening market access are some of the major drivers to this growth. China’s rapidly-moving health care industry and unique market characteristics has often required a pharmaceutical company […]
August 8, 2019
antibiotics

Innovations in Antibiotics – Hope or Too Little Too Late?

A brief history Even though Alexander Fleming discovered the first antibiotic penicillin in 1928, it was introduced into the market as a commercial therapeutic for bacterial infection, only in 1940. It was Gerhard Domaghk who developed the first commercial antibacterial Prontosil, a sulfonamide, in 1930s. The introduction of penicillin marked […]
August 2, 2019
Phenotype

Classical Pharmacology is Dead: Long Live Phenotypic Screening!

  The tediously long and risk-laden process of translating a discovery in biology to a marketable medical breakthrough starts with identifying a repertoire of molecules that will bring about the desired effect. What is it, really? Let´s start with the basics – the definition of phenotype itself. A phenotype is […]
July 23, 2019
RNA

Biology’s Central Dogma Has Been Overturned! So What?

In August 2018, patisiran, a first-in-class therapy was approved in the US and EU to treat the polyneuropathy associated with a genetic disease 002D hereditary transthyretin-mediated amyloidosis. The therapy uses small pieces of ribonucleic acid (RNA) to effectively ‘silence’ a faulty gene, without changing the deoxy ribonucleic acid (DNA) of […]
April 14, 2017

China – Drug Approval Reform

China’s Food and Drug Administration has started implementing key reforms that are likely to be a game changer for pharma companies eyeing the Chinese market.  The presentation below highlights the key reforms:     Key Takeaways: Leveling of Phase 1 playing field: Pharma companies can run a phase 1 trial […]