Blogs

egfr_lung_cancer
1L EGFRm+ Lung cancer is rapidly evolving and changing. Tagrisso is leading the pack with ORR of 77% and PFS of 18.9 mos. However, talking about overall survival, Dacomitinib is currently leading with OS of 34.1 mos. As Tagrioss’s final OS data is yet to be declared, the OS in Continue Reading
 Categories : Oncology Posted by Sakshi Saini  
trial_results
Pembrolizumab demonstrated durable anti-tumor activity in various tumors specially Hodgkin Lymphoma (ORR: 50%, mPFS: 12.2 months, 12 month PFS rate: 59.7%). The results indicate further study of pembrolizumab in pediatric patients with particulate interest in Lymphoma Phase 2 Study results confirms PR rate of 72% with that of phase 1 Continue Reading
 Categories : ASCO18, Oncology, Pediatric Oncology Posted by Sakshi Saini  
financial_incentive
  Why is it so difficult to develop drugs for children with cancer? What can be done to stimlate investments in the pediatric oncology space?  These questions are central to a new study published by MIT Sloan researchers that explores new business models for funding drug development to treat pediatric cancers.  The Continue Reading
 Categories : ASCO18, Oncology, Pediatric Oncology Posted by Sakshi Saini  ,
milestone
Research and development within the cancer field is continuously evolving and progressing. This video highlights the biggest milestones within the field of cancer research spanning 170 years —from the advent of general anesthesia opening the door for cancer surgery in the mid-1800s to the first gene therapy for cancer approved by the Continue Reading
 Categories : ASCO18, Oncology Posted by Preeti Parikh  
Lymphoma - ASCO18
Abstract 7504: Activity and tolerabilty of the first-in-class anti-CD47 antibody Hu5F9-G4 (5F9) with rituximab tolerated in relapsed/refractory non-Hodgkin lymphoma: Initial phase 1b/2 results. Conclusion: 5F9 + rituximab is a novel immunotherapy that inhibits a key macrophage/cancer checkpoint. It is well tolerated with no MTD reached and has promising clinical activity Continue Reading
 Categories : ASCO18, Oncology Posted by Sakshi Saini  , ,
Genitourinary cancer - ASCO18
Abstract 5003: Olaparib (Lynparza) combined with abiraterone (Zytiga) in patients with metastatic castration-resistant prostate cancer (mCRPC): a randomized phase II trial Conclusion: This is the first trial to show clinical benefit (increase in PFS) for mCRPC pts treated with a PARP inhibitor combined with abiraterone, regardless of HRRm status. Safety Continue Reading
 Categories : ASCO18, Oncology Posted by Sakshi Saini  , , ,