August 2, 2019
Phenotype

Classical Pharmacology is Dead: Long Live Phenotypic Screening!

  The tediously long and risk-laden process of translating a discovery in biology to a marketable medical breakthrough starts with identifying a repertoire of molecules that will bring about the desired effect. What is it, really? Let´s start with the basics – the definition of phenotype itself. A phenotype is […]
July 23, 2019
RNA

Biology’s Central Dogma Has Been Overturned! So What?

In August 2018, patisiran, a first-in-class therapy was approved in the US and EU to treat the polyneuropathy associated with a genetic disease 002D hereditary transthyretin-mediated amyloidosis. The therapy uses small pieces of ribonucleic acid (RNA) to effectively ‘silence’ a faulty gene, without changing the deoxy ribonucleic acid (DNA) of […]
July 10, 2019
3D Printing

Body Printing or Printing Your Body: A Short Introduction To Bioprinting

Biofabrication can be defined as the production of complex living and non-living biological products from raw materials such as living cells, molecules, extracellular matrices, and biomaterials. – Mironov et al., 2015. First things first…What´s 3D printing? The standard two-dimensional (2D) printing is the act of depositing ink on a 2D […]